Type 2 Diabetes – Bacteria and Kidney Disease In Diabetes

Type 2 Diabetes – Bacteria and Kidney Disease In Diabetes – A particular research has associated the bacteria Helicobacter pylori, (H. pylori), to an increased risk of developing Type 2 diabetes. One of the serious complications of diabetes is kidney disease. Researchers at the Palu Government Hospital and Safuk Health Group in Istanbul, Turkey, looked at protein in the blood of many volunteers diagnosed with Type 2 diabetes. Some of the diabetic volunteers had an infection caused by H. pylori, and some did not. The plan was to determine whether the bacteria could be associated with kidney disease.
Albumin, a protein found in the blood, is supposed to be held in the blood as it transits through the kidneys. When albumin is found in the urine, it is a sign kidney damage has taken place.
Diabetic nephropathy is one disease that can be signalled by albumin in the urine. Microscopic amounts of albumin in the urine can be a sign that diabetic nephropathy is on the way if steps are not taken. The kidney is composed of glomeruli, collections of tubes, including small blood vessels called capillaries. Since H. pylori causes inflammation and can damage blood vessels, it was hypothesized bacterial damage to the capillaries could be behind diabetic nephropathy.
The Turkish study, published in January 2012 in the Turkish Journal of Gastroenterology, included 92 volunteers previously diagnosed with Type 2 diabetes; 53 of whom tested positive for H. pylori. Those whose blood tested positive for H. pylori showed more microscopic albumin in their urine than did those without the bacteria. Anyone infected with H. pylori also had molecules associated with inflammation in their blood.
From the above, researchers concluded inflammation caused by H. pylori could possibly be involved in the development of diabetic nephropathy, and recommended more studies with larger numbers of participants be carried out to discover whether that could be the case.
Diabetic nephropathy is an insidious disease; it can be present for 5 to 10 years before symptoms appear. Once a year most doctors order urine and blood tests for their patients with diabetes. The urine is searched for microscopic amounts of blood while the blood is tested for molecules called urea and creatinine. Urea and creatinine should be removed from the blood by the kidneys, so rising levels can indicate kidney damage. Tests than can be performed when kidney disease is suspected include:
24 hour urine albumin,
blood levels of phosphorus, calcium, potassium, hydrogen carbonate and parathyroid hormone,
red blood cell analysis, and
protein breakdowns of the urine.
Symptoms of kidney disease include:
poor appetite,
fatigue,
general malaise,
headache,
nausea,
vomiting, and
leg swelling.
Some day, perhaps antibiotics will make diabetic nephropathy a thing of the past. In the mean time, take care of your blood sugar levels and ongoing monitoring of your kidney function. It is an essential part of diabetes care. Both high blood sugar and high blood pressure damage the kidneys:diabetes and hypertension are the two most common causes of kidney failure.