Type 2 Diabetes – Diabetes and Slow Wound Healing! – One of the complications of Type 1 and Type 2 diabetes, is the slow healing of wounds. That is why people with diabetes are cautioned to wear well-fitting shoes and take care of their feet; and be seen for any wounds or ulcers that will not heal.
Researchers at the Shanghai Burn Institute, Rui Jin Hospital, and the Shanhai Jiao Tong University School of Medicine in Shanghai, China looked at whether impaired white blood cells could be the cause of impaired wound healing.
Their study, reported on in March 2011 in the journal Wound Repair and Regeneration, looked at a type of white blood cell called a macrophage, and taken from diabetic rats.
Macrophages, whose name means “big eaters” because they eat bacteria, play an active role in healing skin damage in both rats and people. These “big eaters” release important substances that begin and end the wound healing process…
first they release molecules to bring other macrophages to the spot of tissue damage.
then they release growth factors to make cells grow and multiply and to make proteins.
they release other molecules to make a new matrix upon which new cells can live, and,
finally, they release molecules that stop the growing process once healing is complete.
Macrophages taken from diabetic wounds showed an impairment in the initial phases of wound healing.
From this information, it was concluded that finding ways to help the macrophages function normally might help the wound healing process.
Another study, published in the journal Cell Physiology and Biochemistry in 2012, looked at macrophages and wound healing in diabetics.
An investigator at King Saud University in Riyadh, Saudi Arabia, found macrophages from diabetic mice produced fewer of the molecules needed for wound healing than did macrophages from healthy mice, died early, and were impaired in their ability to eat bacteria. When diabetic mice were supplemented with whey protein from camel milk, their ability to release the molecules needed for wound healing was restored and the macrophages lived longer.
At this point the research on macrophages is still preliminary, so it is not time to run out and buy camel’s milk, but isn’t it nice to know research is going on?
At present, keep your macrophages and your wound healing ability in good shape by:
eating a healthy diet,
getting at least some physical activity every day, and
following the medical regimen prescribed for your by your doctor.
Measuring your blood sugar levels and writing down the numbers will give you and your medical advisor, a good idea of how much control you have and what changes might be necessary.